Ruby Mukhtar, 21, a Law student at Glamorgan University, is planning to put collection boxes and posters in local shops and will also keep a collection box at her home on 5 Marlborough Road.
Her sister, Zara Mukhtar, 22, and best friend Sumera Abbas, 21, will also help with the collection.
Ruby said: "I'm hoping to get money for clothes and all the small things that they have lost in the fire.
"I think it's really important to help the people who have been affected.
"I was evacuated from my house on Marlborough road for just one night.
"What I went through in those 24 hours was bad enough, but some people have nothing.
"If we work together as a community, we can help them."
Her sister Zara added: "We can't replace all the big things they've lost but it's the little things in life we want to give to them to make things easier for them."
Among the neighbours they hope to help is Ruby and Zara's Aunty, Parveen Akhtar.
Mrs Akhtar's house was so badly damaged that it had to be demolished.
Ruby said: "My aunty lost her husband last year, and now she's lost her house too.
"I can't even imagine what she is going through."
Ruby's uncle, Mohammed Ishat, 52, also lives on Marlborough Road and described what Mrs Parveen is going through.
"When she saw the gap where her house had been she just cried and cried.
"She's got nothing left, she's lost photographs of her husband and her memories."
BLOB: Anyone who would like to contribute to Ruby's collection can take donations to 5 Marlborough Road.