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- Wales attempting to make it three wins on the spin to keep their title hopes alive.
- Ireland head to the Millennium Stadium on the back of hard-fought wins against Italy, France and England.
- The Irish have a formidable record in Cardiff but Wales, beaten by England in the opener, have not gone a campaign without a home success since 2003.
- Sam Warburton leads Wales for a record 34th time while Paul O'Connell wins his 100th cap.
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