England scrum-half Ben Youngs has been ruled out of the rest of the South Africa tour with a shoulder injury.
The 22-year-old impressed by scoring two tries in the second Test loss to the Springboks on Saturday but head coach Stuart Lancaster has confirmed he can play no further part in the series. Youngs was taken off after 74 minutes of the 36-27 loss in Johannesburg but there was no indication after the game that he had suffered an injury.
Lancaster said: "He has picked up a shoulder injury. He didn't present it until the end of the game obviously but it was only when we got back and he was struggling to move it - he is out of the tour. From our point of view he was excellent for us in the second Test, he really played well and he is devastated."
His withdrawal could offer the chance for Lee Dickson or Danny Care to start next week's third Test in Port Elizabeth while he will be replaced in the squad by Harlequins' Karl Dickson.
Lancaster went on: "Opportunities present themselves for other players - Lee Dickson and Danny Care - and we have got Lee's brother Karl winging in from Alicante. Karl was somewhere in Spain but we have managed to get him to Heathrow and he is on his way now."
Karl Dickson, 29, is flying overnight and will link up with the squad in time to come into consideration for Tuesday's tour match against the Northern Barbarians in Potchefstroom.
He has been summoned just a day after Jonny May of Gloucester was called up to replace injured Harlequins wing George Lowe in the squad.
Bath's Nick Abendanon last week arrived after injury to Quins full-back Mike Brown while London Irish flanker Jamie Gibson replaced London Wasps' Joe Launchbury before the first Test.
Care, 25, has been waiting for the opportunity to resurrect his international career after sitting out the first two Test losses. The Harlequins number nine was dropped for the RBS 6 Nations by Lancaster earlier this year after a series of off-field incidents.
He responded by finishing the domestic season well and then impressed in last week's victory over the Southern Barbarians in Kimberley.