UPDATE: 5.30pm
The A467 is closed in both directions and there is queuing traffic between the Full Moon roundabout and Cwmcarn roundabout.
A diversion is in place via the B4591 in Wattsville, Crosskeys and Pontywaun (the old road which runs parallel with the A467).
UPDATE: 5pm
THE two people were taken to Nevill Hall hospital in Abergavenny after the crash near the Crosskeys Hotel, ambulance chiefs said.
A Welsh Ambulance Service spokeswoman said: “We were called today at approximately 2.30pm to reports of a road traffic collision on the A467 near to the Crosskeys Hotel in Crosskeys.
"We responded with one rapid response vehicle and two emergency ambulances. Two adult patients were treated at the scene before both were taken to Nevill Hall Hospital, Abergavenny.”
3.52pm:
TWO people were taken to hospital after a crash on the A467 at Crosskeys this afternoon.
Firefighters had to cut the casualties out of the vehicles, South Wales Fire and Rescue Service said.
Two fire engines attended the incident shortly after 2.30pm.
A fire service spokeswoman said two people were taken to hospital by ambulance and the firefighters remained at the scene until 3.25pm.
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